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CSV, CSA and GMP Automation Glossary

Short definitions for validation, QA and automation terms used across the GXPLearn.io training platform.

CSV
Computer System Validation — demonstrating through documented lifecycle activity that automated systems are fit for intended use under GMP. Explore in GXPLearn.io training →
CSA
Computer Software Assurance — risk-based software assurance emphasising critical thinking, intended use and proportionate evidence. Explore in GXPLearn.io training →
GMP
Good Manufacturing Practice — quality system requirements for medicines manufacturing, including documented control of processes and systems. Explore in GXPLearn.io training →
GxP
Collective term for Good Practice quality guidelines (GMP, GCP, GLP, etc.) governing regulated life-science activities. Explore in GXPLearn.io training →
DeltaV
A commercial DCS platform. GXPLearn.io uses DeltaV-style educational simulations — not a licensed DeltaV product or emulator. Explore in GXPLearn.io training →
ISA-88
Batch control standard defining hierarchical recipe models (procedure, unit procedure, operation, phase) for repeatable manufacturing. Explore in GXPLearn.io training →
Recipe
Structured batch instructions defining process organisation, parameters and execution logic coordinated at runtime by batch services. Explore in GXPLearn.io training →
Phase
The lowest executable batch object in ISA-88 — acts on equipment, reports status and is orchestrated by higher recipe layers. Explore in GXPLearn.io training →
Unit procedure
ISA-88 layer that organises operations on a specific process unit within a wider batch procedure. Explore in GXPLearn.io training →
Equipment module
Equipment-facing control abstraction that groups devices and phases for coordinated batch execution on a unit. Explore in GXPLearn.io training →
Control module
Lowest-level control entity — typically a valve, loop or device command interface used by phases and equipment modules. Explore in GXPLearn.io training →
Batch record
Documented evidence of how a batch was executed — parameters, alarms, operator actions, sign-offs and linked electronic records. Explore in GXPLearn.io training →
Audit trail
Secure, time-stamped record of who changed what in a system — essential for investigations, data integrity and GMP review. Explore in GXPLearn.io training →
Alarm
Operator notification of an abnormal condition requiring awareness or response — managed by priority, shelving and acknowledgement discipline. Explore in GXPLearn.io training →
Deviation
Departure from an approved instruction, specification or expected result — investigated for impact, root cause and corrective action. Explore in GXPLearn.io training →
Change control
Formal process to assess, approve and implement changes to validated systems with traceable impact on GxP state. Explore in GXPLearn.io training →
Validation evidence
Documented proof that requirements are met — specifications, test results, traceability and summary reports reviewers can follow. Explore in GXPLearn.io training →
Risk-based testing
Scoping verification and validation effort according to risk, intended use and potential impact on patient safety and product quality. Explore in GXPLearn.io training →
Data integrity
Ensuring data is attributable, legible, contemporaneous, original and accurate (ALCOA+) throughout its lifecycle. Explore in GXPLearn.io training →
ALCOA+
Data integrity principles — Attributable, Legible, Contemporaneous, Original, Accurate — plus Complete, Consistent, Enduring and Available. Explore in GXPLearn.io training →
Historian
Time-series data archive for process values — used in batch review, deviation support and validation evidence. Explore in GXPLearn.io training →
HMI
Human-Machine Interface — operator graphics and controls for monitoring and interacting with running batch and process equipment. Explore in GXPLearn.io training →
PLC
Programmable Logic Controller — industrial controller for discrete and sequential logic, often integrated with wider DCS architectures. Explore in GXPLearn.io training →
DCS
Distributed Control System — platform spreading real-time control across plant controllers with centralised engineering and operations. Explore in GXPLearn.io training →
SCADA
Supervisory Control and Data Acquisition — software supervising remote equipment, often paired with PLCs or DCS layers in manufacturing. Explore in GXPLearn.io training →

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